The ULTIMATE Methylation Genetic Test - 78 Gene DNA Markers - Mouth Swab

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This genetic methylation DNA test is ideal for patients looking to find out what supplements they should be taking and what foods / nutrients they require to optimise their health and fitness. The test is a simple, non-invasive cheek swab, suitable for any age. 

The test is a simple, non-invasive cheek swab, suitable for any age. Our test covers the key methylation genes including MTHFR, MTRR, MTR , AHCY , COMT plus we have added 73 more!

Interested in promoting our test and earning commission? Click HERE to join our affiliate program.

Optional Extras:

  • A4 sized colour printed brochure of your methylation results to be posted to you = £35

  • Gift Boxes ( 11” L x 5.7” W X 1.32 D) - choose between Bio Hacking or Red Bow both with gold foiling finish = £10

  • Ordering as a gift? We need patient name, age & gender - everything else you can mark as N/A

  • Have your results translated into French, Polish, Portuguese, Spanish, Indonesian or Arabic - order HERE (order after your inital order)

  • NEW add-on reports can be viewed for Histamine HERE or SKIN HERE

If you wish to purchase multiple tests for people in the same household please add quantity as 1 for each test so that individual patient forms can be completed. You can keep adding multiple tests to the same basket as long as patients reside at the same address. For multiple tests for the same patient you only need to complete the patient form once.

SHIPPING AVAILABLE WORLDWIDE via FedEX - UK Delivery 2 days - Overseas Delivery 2-4 days

Need it FAST? Order via AMAZON PRIME by midnight for next day UK delivery here

FREE for all orders in January - Every Ultimate Methylation Test ordered until 31/1/26 will receive BOTH an additional Histamine & Skin DNA Report worth £210. This is automatically added to every order so nothing further for you to do. As part of our January promotion, we are also offering a £50 discount voucher, emailed to you after your order, to be used against any further follow up test ordered through our website.

£375.00
 
 

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Frequently asked question

What is methylation? When you consume nutrients, your body must convert raw materials into usable forms. Methylation is the key cellular process that acts like billions of tiny switches, turning genes on and off to regulate mood, detoxify hormones, produce energy and support healthy ageing. Because methylation occurs throughout the body, suboptimal methylation can contribute to a wide range of issues.

What does the test tell me? Our 78-gene Genetic Methylation Test looks for variants (SNPs) that can influence how your body processes nutrients and medications. Popularised by Human Biologist and biohacker Gary Brecka, a methylation DNA test highlights predispositions to need more of certain nutrients. Understanding your personal methylation pathways helps you tailor diet, supplements and lifestyle for optimal health.

View full sample report HERE

A genetic methylation test offers data on potential vitamin and mineral deficiencies. Here is a sample of the data you will receive on your genetic requirements for the following;

Vitamin A - Could you be deficient?

Vitamin B12 - How much do you need? Standard B12 or Methylcobalamin - should you be taking methylated vitamins?

Vitamin B9 - Folate or folic acid ? Check out your MTHFR gene to find out if you require methylfolate.

Vitamin C - Do you have a risk of deficiency?

Vitamin D - Are you at increased risk for low circulating levels?

Vitamin E - Variations in the COMT gene may modify the way individuals respond to vitamin E supplementation.

Magnesium - Struggling with sleep / muscle issues / anxiety? Check out your requirements.

Glutathione - The master detoxifier. Does your body need more of it?

Zinc - Immune system low? Perhaps you require additional zinc in your diet / supplement regime.

Choline - Needed for memory, mood, and muscle control - find out if you need to supplement.

Calcium - Dietary calcium is important for growth, maintenance and repair of bone tissue

Iron - Could you suffer with high iron overload or low iron disposition?

Omega 6 & 3, Cholesterol & Triglycerides - Are your genetics working for you or against when it comes to your lipid levels?

Homocysteine - Do your gene variants suggest higher homocysteine levels?

Glycemic Index / Insulin / Fasting glucose - Should you be watching your carb intake? Are you predisposed to cravings. Is snacking beneficial for you?

Lactose Intolerance - Find out if you carry the gene variant which makes this intolerance likely.

Gluten Intolerance - Do you carry the gene variant that indicates a gluten intolerance?

Caffeine sensitivity - How much is safe for you?

Sodium - An essential micronutrient but are you at high risk of blood pressure issues if you consume the wrong type?

Starch - How do you metabolise starch?

Cardiometabolic Health - What types of exercise suit your genetics?

Weight Loss, Hunger & Energy Balance - Are you likely to require more or less calories? Do you have a typical weight loss and hunger responses?

Protein Requirements - How much should you be consuming?

Fat Requirements - What percentage of your daily intake is ideal?

Alcohol Sensitivity - Do you have a typical or heightened response to alcohol?

Motivation to Exercise - Are you more likely to experience a positive mood change from exercise?

Exercise Behaviour - Research shows that genetic differences influence the likelihood of engaging in physical activity - are your genetics working for you?

Power & Strength & Endurance - Do you have the tendency to excel in activities requiring strength & power or endurance?

Muscle Damage & Pain - Do you have an increased susceptibility to muscle damage and pain?

Bone Mass - What is your typical risk for bone fractures?

Achilles Tendon & Rotator Cuff Injury - Do you have an increased risk for injuries in these areas?

This is just a sample of what you can learn by investing in this once in a lifetime genetic test.

This test covers the key methylation genes - MTHFR, MTRR, MTR , AHCY , COMT plus 73 More!

Your DNA never changes so you only need to get this test done once in your lifetime. A methylation test can offer valuable insights to people with hormone issues, cardiovascular disease, psychiatric and mood disorders including ADD, ADHD, depression, anxiety, schizophrenia and autism. The simple answer is yes it is worth getting a genetic methylation test. Finding out if you are genetically predisposed to require more of certain vitamin or nutrient, means your body can perform optimally. How much does a genetic methylation test cost? That will vary depending on what support package you require but a decent test will come in at around £375. Why do people get genetic methylation tests? Methylation tests are all about preventative medicine. By knowing what nutrients your body requires you can prevent future illness and poor health by supplementing, eating and exercising accordingly.

Yes — we ship worldwide on a flat-rate basis. You’ll pay only one delivery charge at checkout per address, regardless of how many kits you order.

  • UK, Guernsey, Isle of Man, Jersey: £3.50 per order
  • Ireland & Netherlands: £30.00 per order
  • Austria, Belgium, Czechia, Croatia, Cyprus, Finland, France, Germany, Greece, Japan, Lithuania, Luxembourg, Malta, Monaco, Serbia, Slovakia, Slovenia, Spain, Sweden: £35.00 per order
  • Albania, Argentina, Bahamas, Bosnia and Herzegovina, Brazil, Canada, Colombia, Denmark, Dominican Republic, Ecuador, Estonia, Gibraltar, Guatemala, Hungary, Iceland, Italy, Kenya, Latvia, Macedonia, Mauritania, Mauritius, Moldova, Paraguay, Portugal, Puerto Rico, Romania, Switzerland, Togo, USA: £40.00 per order
  • Bulgaria, Jamaica, Kyrgyzstan, Morocco, Poland, Taiwan, Turkey, Zimbabwe: £45.00 per order
  • Philippines: £50.00 per order
  • Kuwait: £55.00 per order
  • Australia, Bahrain, Barbados, Bermuda, Cayman Islands, Chile, Egypt, Hong Kong, Indonesia, Jordan, Kosovo, Malaysia, New Zealand, Norway, Oman, Qatar, Saudi Arabia, Singapore, South Africa, Thailand, UAE: £59.00 per order
  • Israel: £65.00 per order

Orders OUTSIDE UK, USA, AUSTRALIA & CANADA - Yes, we can now ship this test all over the world (with the exception of China, India, Mexico, Costa Rica, Iran, Lebanon and Russia). Please select your country at checkout. We use FedEx to deliver our kits, tracking is provided and deliveries usually arrive in 3-4 working days. The test kits are declared as '$2 per kit value' and usually (90% of the time) do not require customs import fees. However, some destination country customs agents may decide (unfortunately, it does seem to be at the discretion of the individual agent) to apply charges, and this is beyond our control and beyond the control of the courier. In the unlikely event this happens, your courier will notify you if an import fee is due before delivering to you. If you are contacted by customs, you should declare the package value as being $2 per test kit which will match the official lab document for a cotton bud swab. We can provide you with a copy of the commercial invoice, if required. We provide approved packaging for the return of the sample, but OUTSIDE UK, USA, AUSTRALIA & CANADA you are responsible for arranging and paying for return postage. All lab reports are provided in English.

You will be asked to fill out a patient form at checkout which will give us more information on your symptoms, current medications and supplement intake to allow us to tailor your protocol to you personally. If you would prefer not to provide this information just write N/A. Ordering as a gift? We require name and gender but other patient details can be marked as N/A.

UK Kit Delivery Time – FedEx courier – 2-3 working days. International delivery available in 3-4 working days worldwide (please note we ship worldwide with the exception of China, India, Iran, Lebanon, Mexico, Costa Rica and Russia)

How do you test for methylation in the UK? The test is a simple, non-invasive oral sample (cheek swab). The only requirement is to abstain from eating, brushing teeth, chewing gum, drinking or smoking for at least 30 minutes before testing. Any lipstick or lip balm should be wiped clean before providing the sample. See instructions HERE. See video instructions for taking sample HERE . There are no special storage or transport requirements and you can return any day of the week. You can take this test at any time of day, there is no need to stop taking medications or supplements prior to taking your sample. As long as cheek swabs are stored in the dry pouch with the desiccant that is provided with the buccal swab kit, samples remain viable for up to 6 months.

No. As we're testing the genetic code, which is fixed, the test is not impacted by illness, infections, medication, the food you eat, or supplements you take. To avoid contamination of the sample, please abstain from eating / drinking for at least 1 hour before methylation DNA testing. Continue taking all your prescription medications and supplements as normal but please note them on your patient form at checkout.

As long as cheek swabs are returned in the buccal swab kit pouch, DNA samples remain viable for up to 6 months on a cotton swab.

The return package provided for these countries has prepaid postage affixed on it so if you live in the UK, USA, Australia or Canada you can simply pop your sample into any postbox for free returns. We do recognise that some patients prefer to send samples via courier for peace of mind. If you choose this option, you will need to pay for return courier fees. We provide return customs paperwork to support you but if you require assistance completing commercial invoices or customs paperwork please do contact info@mybodyfabulous.co.uk

Explore vetted devices, tools and services that complement your methylation protocol.

View Biohacking Partners on our Health Testing Website

The new Ultimate DNA methylation test results format is easy to read with nutritional support included in the lab test so you can choose just the lab results with no support if you prefer.

In ADDITION to your lab results we can provide the following options which are INCLUDED in the package prices:

A) Follow up personalised written report produced by our clinical team (click HERE for team info). Our team will review your results alongside the patient information you have provided us with and highlight dietary, lifestyle and biohacking advice plus links to a personalised supplement protocol, including specific doses and any further testing required. This document is personalised to you and is 3-4 pages long.

OR

B) Follow up 45-minute video call to discuss your results and answer any questions you have. Once the lab has completed your DNA results you will be sent these via email with a link to book a time and day online. We have excellent zoom appointment availability with appointment slots usually available next day. You will also then be given the option to upgrade your 45-minute call to a 60-minute call for an additional £30 if you wish. During the call your practitioner will explain the results in more detail and what they mean for you. You can ask questions and ask the practitioner to focus on the genes that affect your specific health goals if you wish. After your call you are sent a personalised list of supplements & the dose your practitioner advises with links to purchase from our supplements store. This is for your convenience. You are of course welcome to purchase supplements elsewhere. Zoom calls are recorded (unless you request otherwise) and you are sent a link to download your video after your call so you can refer back to this for years to come as a reminder. Please note if the patient is under 18, we require a parent or guardian to be present on the call.

OR

C) Both Zoom call and written report with personalised next steps (Zoom call is first and written report follows).

Once you have ordered via our website you will receive an email notification when your kit has been shipped to you via FedEx with a tracking number. Please allow 2-3 working days for your kit to arrive in UK. You can then freepost your sample back to the lab via Royal Mail 1st class (for UK). Prepaid stamped return envelopes are also included for USA, Australia & Canada. All other international orders are NOT freepost returns so you will need to use the addressed envelope and arrange courier back to the labs. Once you have sent back your sample we will email you to let you know that it has been safely received at the lab and your genotyping has started. Results are then ready in 3 weeks and are emailed to you along with either the link to book your zoom call or your written report. You will not hear from us during the time your sample is being processed unless there is an issue with your sample. Please note that we will email lab results to the email address provided at checkout. If you need to change this information it is your responsibility to contact info@mybodyfabulous.co.uk to request results are sent to an alternative email address.

As an additional extra, if you select to order a printed copy of your results you will receive a personalised A4 size, glossy, colour printed brochure posted to you approximately 2 weeks after your PDF is sent to you.

Each test is processed in the CLIA-certified laboratory. All physical samples are completely destroyed after 6 months. The client report, the data and the DNA sample is never (and will never be) shared with, or sold to third parties

Unlike other companies a real human being reviews your results! Our Genetic specialists will evaluate your patient intake form to ensure they know more about you before prescribing supplements and dietary changes.

Meet our Methylation Experts on our Health Testing Website

Yes! We’re genetic methylation experts and can help you get the most from your results. We recommend a 45-minute video call to review your data and provide a summary and supplement shopping list. Book Support Call

If possible, we recommend you do have a blood test to check your vitamin and mineral levels to optimise your DNA testing. We offer a huge range of testing so when a member of our genetics team is assigned to review your results they may feel you would benefit from other specific testing such as genetic aging testing, hormones (testosterone / estrogen, cortisol , thyroid levels etc), microbiome, food intolerance , amino acids & homocysteine, mould / toxin testing tec. If any additional testing is required, this will be advised in your Zoom call / written report.

Every human has a slightly different genetic makeup. We inherit our gene variants from both parents so although you may have similar genes to your child you will not have identical gene mutations. Our genes are the same from the moment we are born so you only ever need to do this test once in your lifetime and you will have the data on your gene variants for life.

Yes, we provide discounts on methylation testing:

  • Order 2 tests — get 5% off — use code ULT5
  • Order 3 tests — get 7% off — use code ULT7
  • Order 4 or more tests — get 10% off — use code ULT10
  • Order 6 or more tests — get 12% off — use code ULT12
  • Order 10 or more tests — get 15% off — use code ULT15

Please note all tests must be shipped to the same address.

You can not purchase this test anywhere else, we are the sole distributors for this specific set of genes. Established in 2013 we are the UK’s largest functional medicine clinic.

Winner - Health Testing Specialists of The Year 2024-25 - Corporate LiveWire Global

Winner - Biohacking Specialists of the Year 2024 – Healthcare & Pharmaceutical Awards

Winner - Most Trusted Health & Nutrition Clinic 2024 - Southern Enterprise Awards

Winner - Most Innovative Functional Medicine Centre 2024 – Health & Pharma Awards

Winner - Health Testing Clinic of The Year 2023 - Prestige Awards

Read hundreds of positive patient experiences on Google & Trustpilot HERE .

See our lab video HERE health video HERE fitness & performance video HERE

After purchasing, you are also able to access the Body Fabulous Methylation Resource Centre & Private Facebook Group via a private link giving you access to health challenges and dozens of useful data sheets and downloads to support you on your health journey.

Looking for Biohacking devices to use alongside your DNA results? Click HERE to view our recommended partners fo red light, PEMF mats, sleep devices, health monitors and much more.

Our testing is conducted via the same method, i.e cheek swab DNA extraction. It’s just a simple wand to wipe on the inside of your cheeks. Gary Brecka's 10X methylation test covers the main 5 methylation genes COMT, AHCY, MTRR, MTR, MTHFR. We offer exactly the same methylation genetic testing with these top 5 genes plus 73 others to give you information on other nutrients requirements such as zinc, manganese and choline. We will analyse each gene mutation for you and give you an easy to read, personalised report on supplements and dietary changes to support your body.

Gene variants covered:ABCA1 rs1883025, ABCG8 rs6544713, ACE rs4343, ACTN3 rs1815739, ADCY5 rs11708067, ADIPOQ rs17300539, ADIPOQ rs17366568, ADORA2A rs5751876, ADRB2 rs1042713, ADRB3 rs4994, AHCY rs121918608, ALDH2 rs671, AMY1 rs4244372, ANGPTL3 rs10889353, APOA2 rs5082, APOA5 rs12272004, APOA5 rs662799, BCMO1 rs11645428, BDNF rs6265, CD36 rs1761667, CLOCK rs1801260, COL5A1 rs12722, COMT rs4680, CYP17A1 rs743572, CYP19A1 rs10046, CYP19A1 rs2470158, CYP1A2 rs2472300, CYP1B1 rs1056836, CYP2R1 rs10741657, FADS1 rs174547, FTO rs9939609, FUT2 rs601338, GC rs2282679, GC rs4588, GC rs7041, GLUT2 rs5400, GSTP1 rs1695, GSTT1 rs2266633, HFE rs1799945, HFE rs1800562, HLA rs2187668, HLA rs2395182, HLA rs4639334, HLA rs4713586, HLA rs7454108, HLA rs7775228, IL6 rs1800795, IRS1 rs2943641, LEPR rs12405556, LIPC rs1800588, MC4R rs17782313, MCM6 rs4988235, MMP1 rs1799750, MMP3 rs3025058, MTHFD1 rs2236225, MTHFR (A1298C) rs1801131, MTHFR (C677T) rs1801133, MTR rs1805087, MTRR rs1801394, NFIA-AS2 rs1572312, NMB rs1051168, NOS3 rs1799983, NRF2 rs12594956, PEMT rs12325817, PGC1a rs8192678, PPARy2 rs1801282, SLC17A1 rs17342717, SLC30A3 rs11126936, SOD2 rs4880, TCF7L2 rs12255372, TCF7L2 rs7903146, TF rs3811647, TFR2 rs7385804, TMPRSS6 rs4820268, TRPM6 rs11144134, UCP1 rs1800592, UGT2B15 rs1902023, WNT16 rs2707466.

Yes — we can export your 78 gene variants into an Excel spreadsheet and email this to you if required - order HERE.